Prepare roast in slow cooker and set on low just before heading to bed, and it will simmer away while you sleep. Refrigerate in the morning, then microwave for dinner.
Following directions above, stir all ingredients but beef together in an ovenproof saucepan not much larger than the roast. Bring to a boil over high heat, stirring often. Add beef and turn to coat. Cover and roast in centre of preheated 325F (160C) oven until fork-tender, turning meat occasionally, 3 to 4 hours.